产品货号：
Z19032
中文名称：
Junctophilin-3/JPH3抗体
英文名称：
Anti-Junctophilin-3/JPH3 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Junctophilin-3/JPH3 Antibody |
| 指标别名 | JP3,HDL2,JP-3,TNRC22,CAGL237,JP3,Junctophilin-3,Junctophilin type 3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | JPH3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | JPH3 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human JPH3.The immunogen is located within amino acids 540 - 590 of JPH3. |
| 计算分子量 | 81kDa |
| 成分 | JPH3 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | JPH3 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels.Junctophilins (JPs) are important components of the junctional complexes.JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM.Four JPs have been identified as tissue-specific subtypes derived from different genes:JPH1 is expressed in skeletal muscle,JPH2 is detected throughout all muscle cell types,and JPH3 and JPH4 are predominantly expressed in the brain.In the CNS,both JPH3 and JPH4 are expressed throughout neural sites and contribute to the subsurface cistern formation in neurons.Mice lacking both JPH3 and JPH4 subtypes exhibit serious symptoms such as impaired learning and memory and are accompanied by abnormal nervous functions.A repeat expansion in JPH3 is associated with Huntington disease-like 2.At least two isoforms of JPH3 are known to exist. |
| Uniprot ID | Q8WXH2 |
| 基因名全称 | Junctophilin 3 |
| 蛋白名全称 | Junctophilin 3 |
| 推荐稀释比 | JPH3 antibody can be used for detection of JPH3 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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